Psoralea – Bu Gu Zhi

psoralea fruit (Bu Gu Zhi)In traditional Chinese remedies, psoralea fruit (Bu Gu Zhi) is known for its effective treatment for vitiligo. However, the benefits psoralea has are more than that. So, let’s take a closer look at what this amazing herb can do for us.

What is psoralea?

Also known as Fructus Psoraleae Corylifoliae, actually it refers to the seed of Psoralea pinnata. L. or Psoralea corylifolia L. (Psoralea corylifolia Linn.), which is an annual plant growing mainly in provinces of Henan, Anhui, Guangdong, Shanxi, Jiangxi and Sichuan in China. However, it isn’t native to China but west Asia.

The dried psoralea seeds appear mainly as flat ellipse but sometimes shape something like a kidney, 3 to 5mm long, 2 to 4mm in diameter, 1.5mm thick, with a dimple in the middle, and dark brown rough surface with fine reticulate wrinkles and dense glandular spots. The thin pericarp is hard to be peeled off from the testa. Inside there is one kernel and a pair of cotyledon, from light brown to yellowish-brown, and rich in oil. And it has a very light sweet smell and slightly bitter and pungent taste.

The seeds of psoralea coryli folia should be collected when they are ripe in autumn, and then dried in the sun. Medicinally both the raw and the stir-fried with brine are being employed.

What is it used for?

According to Traditional Chinese Medicine (TCM), the properties of Buguzhi are warm, bitter, and acrid. And it covers meridians of kidney pericardium, spleen, stomach, and lung.

Main functions are to tonify kidney yang, respire qi for relieving asthma, and warm spleen for stopping diarrhea. Main uses and indications are deficient kidney yang, deficient cold in lower jiao, cold-pain in low back and knee, ED (erectile dysfunction), nocturnal emission, frequent micturition, enuresis, deficiency of kidney qi failing to control respiring qi, non-stop dyspnea of deficiency type, asthenia of both the spleen and kidney, chronic diarrhea, vitiligo, alopecia areata or hair loss, and psoriasis.

Regular dosage is 6 to 15 grams in decoction, or in wan (teapills) and in San (powder). Externally apply appropriate amount of tinctures on the infected part.

Related Chinese herbal formulas

Thanks to its fabulous healing properties, this herb is widely used in many herbal treatments in TCM. The renowned applications are as follows, to name but a few.

(1). Si Shen Wan (Four Spirits Pill), from Zheng Zhi Zhun Sheng (Standards of Patterns and Treatments) written by Wang Ken-Tang in 1602, is mainly for the cure of fifth-watch diarrhea due to deficient cold in spleen and kidney. Other Chinese herbs are Rou Dou Kou (Nutmeg Seeds), Wu Zhu Yu (Evodia Fruit), and Wu Wei Zi (Schisandra Seed);

(2). Bu Gu Zhi Wan, from Ben Cao Gang Mu (Compendium of Materia Medica) written by Li Shizhen in the Ming Dynasty (1378~1644), is primarily for the remedy of deficiency of lower burner, heavy arms and legs, and profuse night sweat. Other healing herbs are Tu Si Zi (Chinese Dodder Seeds), Hu Tao Ren (Walnut Nut), Ru Xiang (Frankincense), Mo Yao (Myrrh), and Chen Xiang (Aloeswood);

(3). Qing’e Wan, from Tai Ping Hui Min He Ji Ju Fang (Imperial Grace Formulary of the Tai Ping Era) written by the Imperial Medical Department in 1078-1085, is formulated for low back pain caused by deficient kidney. Other medicinal herbs are Du Zhong (Eucommia Bark), Hu Tao Ren, and Da Suan (garlic).

Modern medical applications

Psoraleas contain coumarins, flavonoids, isoflavones, chalcones, lipids, stigmasterol, β-Sitosterol-D-glucoside, daucosterol, triacontane, glucose, volatile oil, and organic acid, etc. And coumarins include psoralen, isopsoralen, angelicin, corylidin, psoralidin, and isopsoralidin; flavonoids include bavachin, isobavachin, and bavachinin; isoflavones include corylin, neobavaisoflavone, and corylinal; chalcones include bavachalcone, isobavachalcone, neobavachalcone, isoneobavachalcone, corylifolinin, and bavachromene, etc.

Psoralea fruit has following functions according to modern pharmacology experimental results.

(1). Dilate or widen the coronary arteries and stimulate hepatopirtic system; induce the formation of erythrocyte and hemoglobin;

(2). Shorten the bleeding time and reduce amount of bleeding in menorrhagia, metrorrhagia, postpartum hemorrhage, nosebleed, bleeding gums, and hemophilia;

(3). Inhibit the growth of staphylococcus aureus, staphylococcus albus, staphylococcus citreus, mycobacterium tuberculosis, and mold;

(4). Fight cancer. The suppression ratio of cervical cancer is as much as 90%;

(5). Kill parasites like trichomonas vaginalis;

(6). Enhance the synthesis of prostaglandin;

(7). Prevent early pregnancy;

(8). Make the skin more sensitive to ultraviolet irradiation and prone to pigmentation;

(9). Promote the flow of bile;

(10). Stay young and strengthen the immune and internal secretion.

Potential side effects and contraindications

Overdose or longer-term use of psoralea was reportedly with some side effects, such as loss of appetite, anemia, leukopenia, and toxic liver injury. So, make sure to consult your physician before taking psoraleas.

TCM wise, taking psoralea fruit for a long time can lead to symptoms like dry mouth and throat because of its warm-dry nature and stomach irritation. So, extreme care should be taken to those diagnosed with fire excess from Yin deficiency and with stomach trouble.

3 thoughts on “Psoralea – Bu Gu Zhi


    I am pleased to read about the medicinal values of the seeds.
    Very useful information and look forward to further articles on
    this seeds and topic.

  2. Lisa

    This is added to a fertility tonic I bought to help me conceive . It says here that it helps prevent early pregnancy ? Any insight on this would be so helpful ! Thank you.

    1. Miriam

      Lisa, I know you posted this ages ago but did you ever find out an answer? I just encountered this same contradiction with some fertility herb concoction. Thanks


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